The third-ranked Serb used his flat groundstrokes to sail through the first set in 22 minutes. He trailed 2-0 in the second set before rallying to win five of the next six games, ending the match with a backhand winner.
"The second set was a bit difficult as I couldn't get the first serve percentage high,'' Djokovic said.
Nicolas Mahut defeated fifth-seed Jarkko Nieminen 6-4, 3-6, 6-3, and sixth-seed Robin Soderling beat Teimuraz Gabashvili 6-1, 6-3. Tomas Berdych joined them in the quarterfinals after defeating Simone Bolelli 7-5, 6-1.