And the 18-year-old was looking to reverse a pattern from her first three trips to this event.
In the men's Regions Morgan Keegan Championships, eighth-seeded Sam Querrey of the United States earned a 7-6 (4) 6-4 win over Germany's Tommy Haas, who won here in 1999.
Top-seeded Andy Roddick and No. 3 James Blake were set for late matches. Blake was facing Lleyton Hewitt.
Wozniacki has been eliminated by the eventual Memphis champion for three straight years - Sofia Arvidsson of Sweden in 2006, and Americans Venus Williams in 2007 and Lindsey Davenport last year. She has yet to get past the quarterfinals in this event.
But in a breakout 2008 season, Wozniacki won three tournaments and vaulted from 68th to 12th in the world rankings. A win here could push her to 11th.
"I'd like to be in the top 10. I'd like to be No. 1,'' she said, "but I'm still working, trying to take each match as it comes, and trying to get better all around. I've still got lots of things I can improve.''
Wozniacki had played the last match of the night on Tuesday, laying a 6-1, 6-2 win over Jelena Dokic of Australia that reversed a loss to the veteran in last month's Australian Open.
The youngster showed few effects during her early afternoon match with Bremond on Wednesday, even though she was extended a bit in the second set.
"I've still got jet lag, so getting up this morning was tough. But once I got on the court I felt great,'' Wozniacki said. "I was concentrating on holding serve more than anything else, because this is a pretty fast hard court, so you have to concentrate.''
In other men's matches, fifth-seeded Radek Stepanek of the Czech Republic defeated Kevin Kim of the United States 6-4, 6-2. Seventh-seed Mardy Fish scored a 6-1, 7-5 victory over Yen-hsun Lu of Taiwan. Philipp Petzschner of Germany defeated Finland's Jarkko Nieminen, 6-3, 6-4. And Robby Ginepri of the United States defeated Simon Greul of Germany 6-4, 6-4 for a possible chance at Roddick.
On the women's side, third-seeded Lucie Safarova of the Czech Republic survived a first-set tiebreaker and eliminated Vania King of the United States 7-6 (1), 6-3 to reach the quarterfinals.
In other second-round play, fourth-seeded Anne Keothavong of Britain also went through a tiebreaker before defeating Michelle Larcher de Brito of Portugal 7-6 (2), 6-4. No. 6 Sabine Lisicki of Germany defeated Stephanie Foretz of France 6-1, 6-4, and eighth-seeded Pauline Parmentier defeated South African qualifier Chanelle Scheepers 6-4, 6-1.
Hewitt upsets Blake; Roddick rolls on
Capello: Spain Are The Best National Team At The Moment
