Struggling to find his rhythm with a new racket, top-seeded Djokovic was upset 6-4, 6-4 in his opening match of the season on Tuesday by the 20-year-old Latvian who finished last year at No. 53.
"I'm not panicking. I'm not seriously a big doubt. The Australian Open is my highest goal for this part of the year,'' Djokovic said. "It's not the end of the world. It's the first match, so I'm still trying not to be very pessimistic.''
The setback gave him more time to prepare for the Australian Open which starts Jan. 19 in Melbourne, added Djokovic, who later confirmed he'd accepted a wild-card entry for next week's Sydney International.
"Let's look on the bright side, it's only the start of the year and the biggest tournament is coming up,'' the 21-year-old Serbian said. "It was disappointing to lose in Brisbane but I now have another chance for more high quality matches in Sydney.''
Second-seeded Jo-Wilfried Tsonga, who lost to Djokovic in the last Australian Open final, beat Argentina's Agustin Calleri 6-2, 7-5 later Tuesday and is now favored to win the inaugural Brisbane title.
Fifth-seeded Tomas Berdych of Czech Republic beat Australian Brydan Klein 6-0, 6-4, No. 7 Richard Gasquet of France beat American Taylor Dent 7-5, 6-4, and No. 4 Robin Soderling of Sweden had a 6-3, 6-3 win over Julien Benneteau in a second-round match.
American qualifiers Amer Delic and Bobby Reynolds both went out. Croatia's Mario Ancic overcame Delic 7-6 (2), 6-7 (4), 7-6 (6) and Japan's Kei Nishikori beat Reynolds 6-3, 6-2.
On the women's side, second-seeded Victoria Azarenka sealed a 7-6 (4), 7-5 win over Jarmila Gajdosova of Slovakia on her third match point and No. 3 Marion Bartoli of France beat Hungary's Melinda Czink 5-7, 6-3, 6-1.
Azarenka, runner-up at the 2008 Gold Coast tournament which was a forerunner to the joint ATP-WTA Brisbane International, thought she'd won on her first match point but was on the receiving end of an erroneous out call on her deep forehand.
She broke Gajdosova at love in the next game to reach a quarterfinal match against Czech Republic's Lucie Safarova, a 6-4, 6-4 winner over Australia's Samantha Stosur.
Djokovic never got on top of Gulbis with his serve. He dropped only one set as he won his first Grand Slam title at Melbourne Park last year, beating Roger Federer in the semifinals and Frenchman Tsonga in the final.
And he started this week as a chance to replace Federer at No. 2 in the rankings and was a hot favorite to improve to 3-0 against Gulbis, both his previous wins coming in quarterfinals last season at the French Open and at Cincinnati.
But he said he had trouble serving with a new racket - he switched from Wilson to Head this season - and that contributed to him being broken in the fifth game.
Both players dropped serve twice to open the second set before Djokovic held for a 3-2 lead, raising both arms in mock triumph when he earned a game point with an ace.
But he was soon in trouble again, dropping serve in the ninth game before Gulbis closed out at love, sealing the win in 1 hour, 28 minutes with an ace, his fourth of the match.
"It's one of my best wins - (but) best games, I don't think so,'' Gulbis said. "I had some beautiful losses, so yeah, it's the best win but not my best game.''
Djokovic's first serve percentage was only 48 and he was broken four times. He said he needed time to get used to the changes.
"I didn't play well. I served really, really bad and couldn't get any rhythm,'' Djokovic said. Gulbis "is young, he's talented and he's got nothing to lose and he used his opportunities.''
The loss had other ramifications for Djokovic, who needed a successful run in Brisbane and for Federer to flop in Doha to move to a career-high No. 2 in the rankings.
"It was not playing a big role at all,'' Djokovic said of the rankings calculations. "It was just a matter of me playing well or not.''
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